Biomanufacturing Supply Chains are unique in their need to account for variability and risk in bulk, fill and packaging production and inventory positioning. We'll describe a different approach to biomanufacturing supply chain planning that optimizes inventory levels and risk strategies in real time. We'll show how by focusing on real-time data from PI, Delta V, Oracle, SAP, Excel and other sources, biomanufacturers can quickly re-plan against real-time events in seconds rather than hours or days.